The articles listed at the permanent link and below have been recommended by six professionals from the Scientific Advisory Council of Naevus Global, spanning most disciplines of relevant expertise. All are significant and classic papers that have advanced knowledge about simple or syndromic congenital melanocytic nevi and their potential complications. We asked volunteers to exclude recommending their own work. In many cases, full text is available online; in others, please contact Naevus Global. We can usually obtain a reprint from the authors or the publisher as needed.

Permanent link to this list, for which one must also enroll for a free account with the U.S. National Center for Biotechnology Information (NCBI):  http://www.ncbi.nlm.nih.gov/myncbi/collections/48453803/

 

OCOMEN, outcomes for Congenital Melanocytic Naevi

 

The flyer explains the aim of the OCOMEN project.

Publication OCOMEN project, April 2020

 

 

 

 

 

 

Ornella Masnari, stigmatization

Publications on “proxy- and self-reported opinions about the role of surgery in children with CMN”, based on the data from our international online survey.
THANK YOU to Nevus Outreach for the grant we have received and to all of you for your support!! February 2020

• Surgical treatment of children and youth with congenital melanocytic nevi: self? and proxy?reported opinions
• Skin-related quality of life in children and adolescents with congenital melanocytic naevi – an analysis of self- and parent reports
• Predictors of Health-related Quality of Life and Psychological Adjustment in Children and Adolescents With Congenital Melanocytic Nevi: Analysis of Parent Reports

 

 

Publications before 2015

• Adler, N., Dorafshar, A.H., Bauer, B.S., Hoadley, S., Tournell, M., 2009. Tissue expander infections in pediatric patients: management and outcomes. Plast. Reconstr. Surg. 124, 484–489.
• Bastian, B.C., Xiong, J., Frieden, I.J., Williams, M.L., Chou, P., Busam, K., Pinkel, D., LeBoit, P.E., 2002. Genetic changes in neoplasms arising in congenital melanocytic nevi: differences between nodular proliferations and melanomas. Am. J. Pathol. 161, 1163–9.
• Bauer, B.S., Corcoran, J., 2005. Treatment of large and giant nevi. Clin. Plast. Surg. 32, 11–8, vii.
• Bauer, B.S., Dickie, S.R., Marghoob, A.A., 2014. The shifting paradigm in the management of giant congenital melanocytic nevi: review and clinical applications. Plast. Reconstr. Surg. 134, 658e–659e.
• Bauer, B.S., Margulis, A., 2004. The expanded transposition flap: shifting paradigms based on experience gained from two decades of pediatric tissue expansion. Plast. Reconstr. Surg. 114, 98–106.
• Bauer, J., Curtin, J.A., Pinkel, D., Bastian, B.C., 2007. Congenital melanocytic nevi frequently harbor NRAS mutations but no BRAF mutations. J. Invest. Dermatol. 127, 179–82.
• Bett, B.J., 2005. Large or multiple congenital melanocytic nevi: occurrence of cutaneous melanoma in 1008 persons. J. Am. Acad. Dermatol. 52, 793–7.
• Bittencourt, F. V, Marghoob, A.A., Kopf, A.W., Koenig, K.L., Bart, R.S., 2000. Large congenital melanocytic nevi and the risk for development of malignant melanoma and neurocutaneous melanocytosis. Pediatrics 106, 736–741.
• Charbel, C., Fontaine, R.H., Kadlub, N., Coulomb-L’Hermine, A., Rouillé, T., How-Kit, A., Moguelet, P., Tost, J., Picard, A., Aractingi, S., Guégan, S., 2015. Clonogenic cell subpopulations maintain congenital melanocytic nevi. J. Invest. Dermatol. 135, 824–833.
• Charbel, C., Fontaine, R.H., Malouf, G.G., Picard, A., Kadlub, N., El-Murr, N., How-Kit, A., Su, X., Coulomb-L’hermine, A., Tost, J., Mourah, S., Aractingi, S., Guégan, S., 2014. NRAS mutation is the sole recurrent somatic mutation in large congenital melanocytic nevi. J. Invest. Dermatol. 134, 1067–74.
• Delmas, V., Beermann, F., Martinozzi, S., Carreira, S., Ackermann, J., Kumasaka, M., Denat, L., Goodall, J., Luciani, F., Viros, A., Demirkan, N., Bastian, B.C., Goding, C.R., Larue, L., 2007. Beta-catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development. Genes Dev. 21, 2923–35.
• Gosain, A.K., Santoro, T.D., Larson, D.L., Gingrass, R.P., 2001. Giant congenital nevi: a 20-year experience and an algorithm for their management. Plast. Reconstr. Surg. 108, 622–636.
• Gur, E., Zuker, R.M., 2000. Complex facial nevi: a surgical algorithm. Plast. Reconstr. Surg. 106, 25–35.
  • Also see: http://www.sciencedirect.com/science/article/pii/S2213653315001032
• Hale, E.K., Stein, J., Ben-Porat, L., Panageas, K.S., Eichenbaum, M.S., Marghoob, A.A., Osman, I., Kopf, A.W., Polsky, D., 2005. Association of melanoma and neurocutaneous melanocytosis with large congenital melanocytic naevi–results from the NYU-LCMN registry. Br. J. Dermatol. 152, 512–7.
• Kadonaga, J.N., Frieden, I.J., 1991. Neurocutaneous melanosis: definition and review of the literature. J. Am. Acad. Dermatol. 24, 747–55.
• Kinsler, V.A., Thomas, A.C., Ishida, M., Bulstrode, N.W., Loughlin, S., Hing, S., Chalker, J., McKenzie, K., Abu-Amero, S., Slater, O., Chanudet, E., Palmer, R., Morrogh, D., Stanier, P., Healy, E., Sebire, N.J., Moore, G.E., 2013. Multiple congenital melanocytic nevi and neurocutaneous melanosis are caused by postzygotic mutations in codon 61 of NRAS. J. Invest. Dermatol. 133, 2229-36.
• Koot, H.M., Waard-Van Der Spek, F. De, Peer, C.D., Mulder, P.G.H., Oranje, a P., 2000. Psychosocial sequelae in 29 children with giant congenital melanocytic naevi. Clin. Exp. Dermatol. 25, 589–593.
• Krengel, S., Hauschild, A., Schäfer, T., 2006. Melanoma risk in congenital melanocytic naevi: a systematic review. Br. J. Dermatol. 155, 1–8.
• Krengel, S., Scope, A., Dusza, S.W., Vonthein, R., Marghoob, A.A., 2013. New recommendations for the categorization of cutaneous features of congenital melanocytic nevi. J. Am. Acad. Dermatol. 68, 441–51.
  • Summarized at this link: http://www.nevus.org/new-cmn-categories-proposed_id767.html
• Kryger, Z.B., Bauer, B.S., 2008. Surgical management of large and giant congenital pigmented nevi of the lower extremity. Plast. Reconstr. Surg. 121, 1674–1684.
• Küsters-Vandevelde, H.V., Willemsen, A.E., Groenen, P.J., Küsters, B., Lammens, M., Wesseling, P., Djafarihamedani, M., Rijntjes, J., Delye, H., Willemsen, M.A., van Herpen, C.M., Blokx, W.A., 2014. Experimental treatment of NRAS-mutated neurocutaneous melanocytosis with MEK162, a MEK-inhibitor. Acta Neuropathol. Commun. 2, 41.
• Lacoste, C., Avril, M.-F., Frassati-Biaggi, A., Dupin, N., Chrétien-Marquet, B., Mahé, E., Bodemer, C., Vergier, B., de la Fouchardière, A., Fraitag, S., 2015. Malignant Melanoma Arising in Patients with a Large Congenital Melanocytic Naevus: Retrospective Study of 10 Cases with Cytogenetic Analysis. Acta Derm. Venereol. 95, 686–90.
• Lim, Y.H., Ovejero, D., Sugarman, J.S., Deklotz, C.M.C., Maruri, A., Eichenfield, L.F., Kelley, P.K., Jüppner, H., Gottschalk, M., Tifft, C.J., Gafni, R.I., Boyce, A.M., Cowen, E.W., Bhattacharyya, N., Guthrie, L.C., Gahl, W. A, Golas, G., Loring, E.C., Overton, J.D., Mane, S.M., Lifton, R.P., Levy, M.L., Collins, M.T., Choate, K. A, 2014. Multilineage somatic activating mutations in HRAS and NRAS cause mosaic cutaneous and skeletal lesions, elevated FGF23 and hypophosphatemia. Hum. Mol. Genet. 23, 397–407.
• Lu, C., Zhang, J., Nagahawatte, P., Easton, J., Lee, S., Liu, Z., Ding, L., Wyczalkowski, M.A., Valentine, M., Navid, F., Mulder, H., Tatevossian, R.G., Dalton, J., Davenport, J., Yin, Z., Edmonson, M., Rusch, M., Wu, G., Li, Y., Parker, M., Hedlund, E., Shurtleff, S., Raimondi, S., Bhavin, V., Donald, Y., Mardis, E.R., Wilson, R.K., Evans, W.E., Ellison, D.W., Pounds, S., Dyer, M., Downing, J.R., Pappo, A., Bahrami, A., 2015. The genomic landscape of childhood and adolescent melanoma. J. Invest. Dermatol. 135, 816–23.
• Marghoob, A.A., Dusza, S., Oliveria, S., Halpern, A., 2004. Number of satellite nevi as a correlate for neurocutaneous melanocytosis in patients with large congenital melanocytic nevi. Arch. Dermatol. 140, 171–5.
• Margulis, A., Bauer, B.S., Corcoran, J.F., 2003. Surgical management of the cutaneous manifestations of linear nevus sebaceus syndrome., Plast. Reconstr. Surg., 111, 1043-50.
• Masnari, O., Landolt, M.A., Roessler, J., Weingaertner, S.K., Neuhaus, K., Meuli, M., Schiestl, C., 2012. Self- and parent-perceived stigmatisation in children and adolescents with congenital or acquired facial differences. J. Plast. Reconstr. Aesthetic Surg. 65, 1664–70.
• Pawlikowski, J.S., Brock, C., Chen, S., Al-Olabi, L., Nixon, C., McGregor, F., Paine, S., Chanudet, E., Lambie, W., Holmes, W.M., Mullin, J.M., Richmond, A., Wu, H., Blyth, K., King, A., Kinsler, V.A., Adams, P.D., 2015. Acute inhibition of MEK suppresses congenital melanocytic nevus syndrome in a murine model driven by activated NRAS and Wnt signaling. J. Invest. Dermatol. 135, 2093–101.
• Pedersen, M., Küsters-Vandevelde, H.V.N., Viros, A., Groenen, P.J.T.A., Sanchez-Laorden, B., Gilhuis, J.H., van Engen-van Grunsven, I.A., Renier, W., Schieving, J., Niculescu-Duvaz, I., Springer, C.J., Küsters, B., Wesseling, P., Blokx, W.A.M., Marais, R., 2013. Primary melanoma of the CNS in children is driven by congenital expression of oncogenic NRAS in melanocytes. Cancer Discov. 3, 458–469.
• Salgado, C.M., Silver, R.B., Bauer, B.S., Basu, D., Schmitt, L., Khakoo, Y., Reyes-Múgica, M., 2014. Skin of patients with large/giant congenital melanocytic nevi shows increased mast cells. Pediatr. Dev. Pathol. 17, 198–203.
• Shakhova, O., Zingg, D., Schaefer, S.M., Hari, L., Civenni, G., Blunschi, J., Claudinot, S., Okoniewski, M., Beermann, F., Mihic-Probst, D., Moch, H., Wegner, M., Dummer, R., Barrandon, Y., Cinelli, P., Sommer, L., 2012. Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma. Nat. Cell Biol. 14, 1–9.
• Vourc’h-Jourdain, M., Martin, L., Barbarot, S., 2013. Large congenital melanocytic nevi: Therapeutic management and melanoma risk: A systematic review. J. Am. Acad. Dermatol. 68, 493–498.e14.